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I have not taking any medication yet for MTHFR which are: methylcobalamin 5mg, 5-methyltetrahydrofolic acid 800mg, P-5-P 50mg
References Seiwerth S, Brcic L, Vuletic LB, Kolenc D, Aralica G, Misic M, Zenko A, Drmic D, Rucman R, Sikiric P
Perry, T
Notably, leonurine, a major alkaloid component, modulates the gut microbiota by enhancing the abundance of beneficial bacteria and raising butyrate levels
Further, MCAS can make one more sensitive to both foods and other substances including herbs, supplements and medications
In these cases, consistency is more important than the specific hour you take your dose
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