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Beyond their effects on insulin secretion, GLP-1 agonists suppress glucagon release from pancreatic alpha cells, slow gastric emptying, and promote satiety through central nervous system pathways

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By activating both GIP and GLP-1 receptors, Tirzepatide increases insulin release when blood sugar is high, lowers the amount of sugar produced by the liver, slows down digestion to help you feel full longer, and reduces appetite, leading to lower food intake

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