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High-resolution X-ray crystal structures of human D crystallin (1.25 A) and the R58H mutant (1.15 A) associated with aculeiform cataract

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Neuroprotection and brain injury repair&Research on metabolic disease models Cerebral ischemia model: After occlusion of the middle cerebral artery (MCAO) in rats, injection of IGF-1 LR3 (10 g/kg) into the lateral ventricle can: Reduce the area of neuronal death by 30%

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If it senses excessively high levels of IGF-1, it can signal the hypothalamus to stop producing GHRH and the pituitary to stop responding to it