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Data availability Anonymized individual participant data may be made available along with the trial protocol
Mechanistic studies are also needed to further explore how GLP-1 RAs influence neural circuits implicated in reward, and reinforcement
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Emerging strategies for engineering Escherichia coli Nissle 1917-based therapeutics
Post-cholecystectomy patients with reduced GLP-1 receptor sensitivity may need higher final doses or dual-compound options to achieve weight loss goals
Meta-analyses and trials in adults have consistently shown that GLP-1 RA therapy lowers body weight by 5%15% depending on agent and dose (17, 24)
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