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Notably, patients who underwent RYGB exhibited a significant elevation in circulating GLP-2 levels at 3 months postoperatively compared to baseline ( p = 0.02), with this difference remaining significant at 6 months ( p = 0.03)
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More serious adverse effects are rare
If problems come up, small changes in eating or exercise can help avoid larger gains
maintain adequate hydration to prevent secondary renal strain
Since semaglutide further slows gastric emptying as part of its mechanism of action, patients with pre-existing gastroparesis may experience worsening of symptoms including nausea, vomiting, bloating, and abdominal discomfort
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