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Older people usually produce less stomach acid and therefore less intrinsic factor, increasing their risk for deficiency
Medications : Some medications, including common antacids and certain type 2 diabetes drugs, can interfere with B12 absorption
Cartilage & Joint Protection Because DSIP is often studied for sleep regulation , it is natural to compare it with melatonin , the most widely used sleep supplement: AOD-9604 demonstrated chondroprotective effects in models of cartilage degradation. May reduce proteoglycan loss and support collagen maintenance
We might change the dose if: Patients dont get better or keep having symptoms of deficiency They keep having trouble absorbing nutrients Their health changes or they get new health problems By watching both lab results and how patients feel, we can make Vitamin B12 shots work best for them
PMID 25875118
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