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Targeted metabolomics reveals PFKFB3 as a key target for elemene-mediated inhibition of glycolysis in prostate cancer cells

Gastrointestinal adverse events were predominantly limited to initial dosing, while dose escalation resulted in lower discontinuation rates owing to these adverse events than among patients who remained on the starting dose

Hormones fluctuate, sleep gets disrupted, recovery feels harder, and body composition can change even when nothing else does

To determine whether GLP-1 produced in pancreatic islets is a target for DPP-4 inhibitors, Gcg was reactivated in alpha cells of Gcg RA Null mice by crossing Gcg- null mice to PDX1Cre mice to generate Gcg RA PDX1Cre mice

Supports mitochondrial function and energy metabolism

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