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CBS) or via xCT inhibition
DOPE is often conjugated with cholesteryl hemisuccinate (CHEMS), forming a stable bilayer at physiological pH that becomes destabilized in acidic environments, such as endosomes or the tumor microenvironment, thereby promoting membrane fusion and facilitating drug release [83]
Annals of Pharmacotherapy
USA 102 , 29342939 (2005)
Results This study enabled mapping a comprehensive metabolome atlas up to 825 metabolites in human myometrium and uterine fibroid tissues via combining UHPLC-MS with GC-MS
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