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The study also developed and validated analytical methods for detecting AOD9604 and its metabolites in biological samples, providing a framework for anti-doping testing

A faster metabolism may lead to quicker absorption and utilization, potentially speeding up the onset of benefits

The mechanistic plausibility is strong (NNMT inhibition increases NAD+ without the gastrointestinal side effects of high-dose nicotinamide), and the short-term tolerability profile is excellent, but we mean this sincerely: if you're using this compound for durations beyond what the published trials covered, you are operating in uncharted territory

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