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A prospective, observational, multicenter study was conducted in more than 40,000 Chinese adults with knee osteoarthritis and type 2 diabetes mellitus [22]
Call 999 or go to A&E immediately if you experience: Severe difficulty breathing or stridor (a high-pitched sound when breathing) Severe swelling in the throat or neck Drooling or inability to swallow liquids Severe chest pain Contact your GP or NHS 111 if you experience: Severe or worsening throat pain that interferes with swallowing or speaking Difficulty swallowing (dysphagia) , particularly if progressive or associated with pain Persistent symptoms not improving after a week High fever (38C or above) accompanying throat symptoms Visible swelling in the neck or throat Blood in saliva or phlegm Hoarseness lasting more than 3 weeks Severe symptoms of reflux , including persistent heartburn, regurgitation, or chest pain Unintentional weight loss beyond your treatment goals, or inability to maintain adequate nutrition Signs of dehydration , such as reduced urine output, dizziness, or extreme thirst Your GP will conduct a thorough assessment, which may include examination of your throat, neck, and lymph nodes
The clinical data available for Ozempic does indicate that gastrointestinal side effects, such as nausea, are more prevalent at higher doses
It can also increase the risk of developing kidney stones
Symptoms may be more noticeable during treatment initiation or dose escalation
InTech, London, pp 931 Matamoros MA, Saiz A, Peuelas M, Bustos-Sanmamed P, Mulet JM, Barjaet MV et al (2015) Function of glutathione peroxidases in legume root nodules
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