Studies show that GLP-1 weight loss drugs can reduce the risk of future health issueslike diabetes, high blood pressure, heart attacks, and strokesby up to 20% (Lancet, 2021)
Given the similarities between the brain's and retina's vascular systems, these findings suggest that GLP-1R agonism could also protect the brain's microvasculature, preserving the integrity of the blood-brain barrier and improving cerebral blood flow
Central Nervous System Appetite Modulation GLP-1 signaling also influences neural pathways involved in hunger and reward processing, as documented in clinical pharmacology research published in the NCBI [2] literature on incretin-based therapies
Walk away this means the lab didn't separate the compounds
Notably, GLP-1R is abundantly expressed in various brain regions, including the hypothalamus, cortex, and hippocampus, as well as peripheral nervous tissues [10]
If youre considering trying one of these diabetes medications for weight loss or better blood sugar control, you may be curious about the differences between Mounjaro and Ozempic, including how they work, their results, safety, side effects, and more