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The triple comparison of semaglutide, tirzepatide, and retatrutide covers the available evidence for each agent

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Drug interaction potential extends beyond these two medications

These follow-on patents form a systematic attempt to add barriers of entry for generic competitors, with the intention of extending Novos market monopoly for as long as possible when the main compound patent on the underlying active ingredient, semaglutide, expires

That's one reason people with high blood pressure can access the drug at a lower BMI than people living with obesity alone (27 versus 30)

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