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In this review, we review the evidence supporting combined SGLT2i and GLP-1RA therapy in type 2 diabetes with a focus on cardiometabolic outcomes, and we propose a pragmatic framework for clinical use
Empagliflozin in heart failure: diuretic and cardiorenal effects
Rare but serious: seizures (mainly in people with seizure disorders), severe allergic reaction with swelling or trouble breathing
2 Pathophysiological basis: coupling of metabolic imbalance and reproductive axis 2.1 Heterogeneous phenotypes and neuroendocrine characteristics of PCOS Polycystic Ovary Syndrome is a clinically heterogeneous syndrome, and diagnosis remains syndromic: clinicians identify combinations of hyperandrogenism, ovulatory dysfunction, and polycystic ovarian morphology (PCOM), while excluding disorders with similar presentations (49)
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