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These medications have been shown to slow gastric emptying, which can enhance feelings of satiety and reduce calorie intake

This was done intentionally to avoid issues of applying a single standard cutoff value across various populations and communities

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"Online options for weight loss can be a predatory space given the stigma and bias many of these individuals have experienced," said Dr Nicole Wilde, an Auckland physician who specialises in obesity medicine

SOUL is the largest GLP-1 trial to include a prespecified secondary analysis of outcomes by concomitant sodium-glucose cotransporter-2 (SGLT2) inhibitor use, noted Nikolaus Marx, MD, Professor of Cardiology and Head of Internal Medicine, University Hospital Aachen, Germany

Timing Follow-up Marker Blood pressure and resting heart rate Why it matters Adds cardiovascular context during body-weight and appetite changes