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However, Gclc KO mice still lost substantial weight while on an HFD, although to a lesser extent than normal chow (Fig

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The Detoxification Advantage Beyond antioxidant protection, glutathione serves as the body's primary detoxification agent

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Cytotoxic T-lymphocyte clones, established by stimulation with the HLA-A2 binding p5365-73 wild type peptide loaded on dendritic cells In vitro, specifically recognize and lyse HLA-A2 tumour cells overexpressing the p53 protein

This phenomenon underscores a critical, systems-level resistance mechanism: signaling network adaptation