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A strong combination for patients over 50 or those with concurrent fatigue and cognitive concerns

The compound is an engineered antagonist designed to disrupt the natural interaction between the intracellular protein foxo4 and the p53 tumor suppressor protein

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Miwa S, Kashyap S, Chini E, von Zglinicki T

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Melatonin with HO also increased non-mitochondrial respiration and proton leak compared to HO alone (Fig