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Its ability to modulate gene expression, promote balanced tissue remodeling, and support regenerative processes makes it particularly interesting for wound healing, skin rejuvenation, and potentially neurodegenerative conditions
As a result, an uptick in the clinical and healthcare burdens related to this complication is expected in the coming years that will greatly affect the healthcare systems.1 In Mexico in 2009, the Clinical guidelines on HE diagnosis and treatment were published in 3 parts, divided into (1) generalities,2 (2) pathophysiology and diagnosis,3 and (3) treatment and future perspectives.4 After nearly 14 years, an update is now indispensable, given the scientific advances that have come about over that period of time, resulting in numerous new developments in diagnostic and therapeutic tools that are now essential for daily clinical practice
SCFAs can cross the BBB via monocarboxylate transporters on endothelial cells, enhancing BBB integrity by upregulating tight junction proteins [137]
Perovic, D., Kolenc, D., Bilic, V., Somun, N., Drmic, D., Elabjer, E., Buljat, G., Seiwerth, S., & Sikiric, P
TB-500 mechanism: Promotes systemic healing through actin regulation, stem cell mobilization, and anti-inflammatory cytokine signaling