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Novo Nordisk filed an NDA for the CagriSema combination in December 2025, with an FDA decision anticipated in late 2026

However, scores on other tests of brain function did not differ

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There is currently no FDA-approved indication for tirzepatide specifically for Hashimoto's disease, and no large-scale randomized controlled trials have evaluated tirzepatide as a treatment for this autoimmune thyroid condition

Thymosin beta4 reduces cardiac fibrosis and improves cardiac function in dystrophic mice