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Higher-order structure characterisation through techniques such as NMR, circular dichroism (CD), and FTIR Stability studies to assess degradation pathways including oxidation, deamidation, and oligomerisation Importantly, formulation components can interfere with detection (e.g., UV-active excipients), requiring careful method design and sample preparation strategies such as buffer exchange
For cost: this is the stronger case
Hurst, C
Any extra materials required for research, such as solvents or diluents, must be obtained separately
M.Lafuente-Ibez de MendozaI.WarnakulasuriyaS
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