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Interaction effects between the nutritional state and carnitine levels were observed in the mRNA levels of ACC, FAS , and DGAT2 in liver and muscle, and ATGL and LPL in liver (Supplemental Table 3), showing nutritional state and L-carnitine both regulated the lipid synthesis and lipolysis
The other two-thirds appears to come from direct effects on inflammation, vascular function, and blood pressure
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High fasting insulin despite normal glucose suggests early insulin resistance before glucose itself becomes abnormal
