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Nat Rev Endocrinol 10(5):261275

In healthy population (n=299;18-70 year-olds) redox metabolites follow normal distribution in blood and remain unchanged during aging

4.2.1 The potential of EVs in the pathogenesis of ocular tumor RB is the most common eye cancer in children, caused by loss of function mutation in the RB1 gene located in chromosome 13 (13q14) (200, 201)