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For the purpose of this review, separate MMRM analyses were performed for the three phase 3a SCALE trials [38] and, in general, the treatment effects estimated using the MMRM analysis method were larger than those estimated using LOCF (Table 2)
ClinicalTrials.gov identifier: NCT03693430
High-dose therapy may also cause a brief increase in blood pressure, though this usually returns to baseline within a few hours
The American Journal of Medicine
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