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Participants were randomized to placebo or one of six retatrutide dose cohorts and treated for 48 weeks
Pleiotropic effects of GLP-1 receptor agonists on peripheral artery disease: Is there any hope
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Sullivan et al., 2000) of phosphorylative cascade, MAPKs (Filomeni et al., 2005c
However, this transition involves distinct pharmacological mechanismssemaglutide activates GLP-1 receptors alone, while tirzepatide activates both GLP-1 and GIP receptors
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