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Acknowledgments We thank Haiyan Yu, Xiaomin Zhao and Yuyu Guo from Core Facilities for Life and Environmental Sciences of SKLMT (State Key Laboratory of Microbial Technology, Shandong University) for the assistance in LSM900 Super Resolution Laser Scanning Confocal Microscope analysis

Hair Follicle Research: Some laboratories apply GHK-Cu spray in follicle-size and hair-cycle observation models, tracking anagen-phase duration across treated groups

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Conclusion: Berberine proved to be a powerful natural alternative for regulating both blood sugar and appetite through GLP-1 stimulation