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BPC-157 demonstrates exceptional safety in animal toxicology studies, with comprehensive evaluations in mice, rats, rabbits, and dogs failing to establish a lethal dose (LD) across wide dose ranges extending from standard research doses (6 g/kg) to levels exceeding 1000-fold higher concentrations (20 mg/kg), with no evidence of acute toxicity, organ-specific damage, or systemic adverse effects even following repeated high-dose administration

BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide derived from a partial sequence of a gastric body protection protein

References Pyo HK, Yoo HG, Won CH, Lee SH, Kang YJ, Eun HC, Cho KH, Kim KH

Dutasteride inhibits both type 1 and type 2 5-alpha reductase enzymes, making it a more potent DHT blocker than finasteride (which targets only type 2)

Resources C.-H

Published data on isoform-specific NOS involvement remain variable and should not be generalized across all cell types or all preclinical models