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Three reviewers (RZ, QH, PS) graded the strength of evidence as high, moderate, low and very low degree, following five assessment criteria which were risk of bias, inconsistency, indirectness, publication bias, and imprecision

Many people assume they can stop once the weight is gone

Over time, this combination of reduced hunger and prolonged fullness can support steady, sustainable weight loss when combined with healthy eating and lifestyle habits

BMJ 343 , d5928 (2011) J.P

This conclusion follows directly from mass balance and clearance kinetics and does not depend on assumptions about specific delivery technologies