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The New England Journal of Medicine, 385 , 503-515
How PEG-MGF Works PEG shield against proteolysis The polyethylene glycol moiety protects MGF from rapid enzymatic breakdown, maintaining circulating levels for hours rather than minutes
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It may be a good choice for patients who need GLP-1 therapy but prefer to avoid injections
GSTs are involved in the main detoxification route of AFB1- exo -8,9-epoxide by catalyzing the conjugation of AFB1- exo -8,9-epoxide to endogenous GSH