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Safety Considerations, Side Effects, and MHRA Guidance Both agents most commonly cause gastrointestinal side effects

2022 (atherosclerosis RCT): A clinical trial in 157 individuals aged 5875 with metabolic syndrome who received 1 g L-carnitine or placebo twice daily for 6 months found that total cholesterol and LDL cholesterol levels were higher in participants taking L-carnitine

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A subcutaneous injection is often the preferred method of administration for vitamin B12 and similar supplements