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Efficacy and safety of liraglutide versus placebo as add-on to glucose-lowering therapy in patients with type 2 diabetes and moderate renal impairment (LIRA-RENAL): a randomized clinical trial

It is more stable in plasma than GSH and, unlike GSH, can be taken up into cells, where it is converted to GSH by intracellular thioesterases

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It is important to note, however, that Retatrutide is still in Phase 3 clinical trials (the TRIUMPH programme), and its full regulatory approval is expected in 20262027