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In order to encourage our bodies to drop fat vs muscle, we have to be sending the right signals

While semaglutide toxicity is rare, doubling up on doses can lead to prolonged gastrointestinal distress that lasts several days

Nevertheless, empagliflozin consistently slowed eGFR decline compared with placebo across all subgroups [48]

doi:10.1001/jamapsychiatry.2025.4308 Hendershot CS, Bremmer MP, Paladino MB, Kostantinis G, Gilmore TA, Sullivan NR, Tow AC, Dermody SS, Prince MA, Jordan R, McKee SA, Fletcher PJ, Claus ED, Klein KR

While this is usually negligible, it can add up over multiple doses from the same vial

Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardio-vascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial