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Some adverse effects reported were irritation of nasal passages, headaches, and a bloody nose

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The compound was originally derived from the natural pineal-gland-extract complex epithalamin, and research has investigated whether AEDG retains some of the parent extract's effects on melatonin biosynthesis and pineal-gland function

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doi: 10.1158/1078-0432.CCR-18-1226 62 MiuraKKodamaYInokuchiSSchnablBAoyamaTOhnishiHet al

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For many patients, this is a powerful first step toward relief

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