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05 Historical and Investigational Context Lipoic acid injections have been described historically in the literature as part of the management approach for severe mushroom poisoning, administered alongside supportive medical care.4,14 Intravenous formulations of lipoic acid have also been used in research and clinical settings in Germany and other European countries, where the compound has been investigated for various potential applications

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Many patients become aware of the depigmented macules and patches, especially in sun-exposed areas, during the summer when tanning increases the contrast between involved and uninvolved skin

Wang et al., 2022

- New improved formula helps increase the effectiveness of dark spot removal and skin brightening by 8 times

I., Smith, B