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The British National Formulary (BNF) reflects the manufacturers' advice that these medications should not be used during lactation

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The trial was conducted under the code of ethics of the World Medical Association (Declaration of Helsinki) for studies involving human subjects

Other Contributing Factors A few other things can make this side effect more likely or more severe: Not drinking enough water throughout the day A diet low in fiber from fruits, vegetables, and whole grains Reduced physical activity or a more sedentary routine Taking other medications that are known to slow digestion, such as certain pain relievers Skipping meals or eating irregularly, which can make digestion less predictable None of these factors are always within your control, but recognizing them can help explain why symptoms may fluctuate from week to week

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