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[] Heavy metals, mainly lead, may also substitute bivalent cations such as calcium ion (Ca2+), magnesium ion (Mg2+), iron (II) (Fe 2 +) and monovalent cations such as sodium ion (Na+) and cause dysfunctions where these cations act as cofactors in various enzyme activities

Larger Trials and Longer-Term Findings Furthermore, a larger RCT of 140 participants observed significant improvements on global symptomatology and general and negative symptoms of schizophrenia in the NAC supplementation (2 g/d

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