Their documented roles range from supporting early microbial colonization and mitigating chronic GI pathologies to enhancing immune function and providing biodefense against specific pathogens (70, 71)
It is also worth being explicit about what documented means here, because it is the load-bearing word for a YMYL page
However, over-nourished, sedentary modern lifestyles disrupt this system and can cause serious medical problems, which include metabolic syndrome, obesity, type 2 diabetes mellitus (T2DM), and cardiovascular disease
Eur J Histochem
This synergy enables researchers to study peptide-mediated interactions across molecular, cellular, and tissue levelsfrom transcriptional modulation and protein signaling to cellular migration and tissue architecture formation
El-Sharaky AS, Wahby MM, Bader EM, Fawzy RA, El-Shahawy IN