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The expiration date can indicate when these supplements have lost significant potency

Current evidence suggests the answer is yes

This keeps B12 levels up as the body heals

It's certainly better than room temperature, but it's not the optimal environment for preserving maximum potency over the long haul

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Even the paperboard used in food packaging (especially if it is recycled cardboard) can contain BPA, which is then transferred to the food we eat.[ref] Related article : BPA, BPS and detoxification pathways These estrogen mimics (at the levels found in people every day) have been linked to increased risk of several estrogen-related conditions, including: endometriosis[ref] enlarged prostate[ref] almost 2-fold increase in breast cancer for higher phthalate exposure (estrogen receptor-positive)[ref] BPA exposure at low levels is linked to increased breast and prostate cancer[ref] uterine fibroids[ref][ref] platelet reactivity and heart disease[ref][ref] We will cover more on how to avoid and eliminate these estrogen mimics in the Lifehacks section