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The least squares mean change compared to placebo is -10.7 with 4 mg retatrutide, -21.6 with 8 mg, and -18.7 with 12 mg
As a result, more and more patients and healthcare professionals will seek information regarding the safety of GLP-1 receptor agonists in the early stages of pregnancy
Importantly, the studies show that tirzepatide does not increase stomach acid production itself
Research Citations Able, C., Liao, B., Saffati, G., et al
GLP-1 medications like semaglutide and tirzepatide have demonstrated weight loss results averaging 15-22% of body weight in clinical trials
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