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One point is where it seems to act
In contrast, Glp1r mRNA was not reduced in lung (which is enriched in GLP-1Rexpressing ECs) (12), other major and minor blood vessels (aortic arch, abdominal aorta, aortic root, carotid artery, portal vein), cardiac chambers (atria, ventricles, interventricular septum), or brain regions such as the brain stem, hypothalamus, cortex, or cerebellum (Figure 1, IL, and Supplemental Figure 1, AL
(from purified sunflower seed lecithin)
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Monitoring for adverse effects requires particular attention
True allergic reactions to GLP-1 receptor agonists are uncommon but documented, and may manifest with pruritus, urticaria, angioedema, or more severe systemic symptoms
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