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GLP-1s are approved for weight loss in adults who have a body mass index of 30 or higher, and those who are overweight with a body mass index of 27 or higher with at least one weight-related health condition such as high blood pressure, high cholesterol and type 2 diabetes

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Efficacy and safety of Mazdutide on weight loss among diabetic and non-diabetic patients: A systematic review and meta-analysis of randomized controlled trials

GLP-1 agonists could lead to worse metabolic health, including significant loss of muscle mass

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