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Goto Y, Su WC, Levy BP, Rixe O, Yang TY, Tolcher AW, et al
Am J Physiol Cell Physiol 2021;320:C37591.ArticlePubMedPMC 6
OMalley GF
Do not exceed recommended dose ** The result depends on individual metabolism
Controversy over the role of DHODH in ferroptosis regulation Although ferroptosis was initially thought to be primarily executed at the plasma membrane, a pivotal study by Boyi Guans group highlighted mitochondria as a potential site of critical lipid peroxidation, particularly under conditions of GPX4 inactivation or in GPX4-low cell lines 23
aeruginosa , low outer membrane permeability is a significant factor contributing to resistance across multiple antibiotic classes
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