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TRPV1 has been shown to be expressed in the brain, -cells (371), nociceptor C fibers, dorsal root ganglia, hepatocytes, spermatozoa (372), airway neurons (373), bladder and urothelium (374), blood vessels, and the whole gastrointestinal myenteric plexus (375), especially in colonic and rectal neurons (376)

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& Mukhopadhyay, A

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MOTS-C improves metabolism by enhancing insulin sensitivity, increasing muscle glucose uptake, and promoting cellular energy production