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Notably, a subset of alpha-cells showed enrichment of alpha-cell maturity markers ( LOXL4 , MAFB , and ARX ), regulators of reduced ER stress ( DDIT3 , XBP1 , and PPP1R15A ), transcription factors governing endocrine fate ( FEV and ISL1 ), receptors involved in glucose homeostasis ( FFAR1 and GPAR119 ), and secretory pathways ( SCG2 ) (68)

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Cellular senescence and inflammaging in age-related diseases

Sulforaphane, an isothiocyanate compound derived from broccoli sprouts and certain cruciferous vegetables, exerts a wide range of beneficial effects in human

Nutritional Habits: Adopting a balanced, reduced-calorie diet is paramount