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Abstract Background: Glucagon-like peptide1 receptor agonists (GLP-1 RAs), such as semaglutide, reduce cardiovascular risk in type 2 diabetes mellitus (T2DM), but the consistency between oral and subcutaneous formulations remains unclear

Compounding is generally permitted only in rare, patient-specific cases where an FDA-approved product cannot be used, such as a documented allergy to an inactive ingredient

Obesity itself is an independent risk factor for venous thromboembolism, increasing risk two to three-fold compared to normal weight