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Trends Microbiol 13:111118 Averyanov AA, Lapikova VP (1990) Activated oxygen as a possible factor in the autoinhibition of spore germination of the fungus Pyricularia oryzae
Oxidative stress-mediated senescence and death of RPE and subsequent death of photoreceptors have been observed in age-related macular degeneration (AMD)
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We also explored several other known regulators of PGC1 activity that are altered in response to 5FU treatment in HCT116, including NRF2, reactive oxygen species and PPAR, but none of these prevented PGC1-driven increases in mitochondrial mass
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