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According to Lillys release, the trial met its primary endpoint: participants titrating up to the highest orforglipron dose lost 27.3 lb (12.4%) of body weight at 72 weeks versus about 0.9% weight loss with placebo

Pregnant or breastfeeding women should seek professional advice before using this product

As Kotaku points out, the companys ad efforts stretch as far back as 2006

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