It is a powerful antioxidant that reduces oxidative stress
Genolet R, Wahli W, Michalik L (2004) PPARs as drug targets to modulate inflammatory responses
While effective, this approach carries risks including supraphysiological hormone levels, suppression of natural GH production, and side effects such as fluid retention, joint pain, carpal tunnel syndrome, and potential insulin resistance
Look for soaps with a high concentration of natural ingredients and avoid those with harsh chemicals or synthetic fragrances
Use comfort-first textures and add soothing/barrier supports Provide a start slow plan for sensitive users Avoid asking consumers to stack too many strong actives at once 5
The FDA's Category 2 designation means the substance may present significant safety risks when used in compounding and is prohibited in compounded medications pending further evaluation