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In the SURMOUNT-1 trial the highest dose produced about 20.9% mean weight loss over 72 weeks

Hausner, H., Derving Karsbl, J., Holst, A

No studies have been conducted on oral semaglutide alternatives like Rybelsus or the Wegovy pill, but because pill versions contain an absorption enhancer to help the drug get through the stomach lining, semaglutide may be more likely to pass through to breast milk

Researchers followed 327 participants for a full year after they stopped taking semaglutide 2.4 mg and ended the structured lifestyle program that accompanied it