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It is studied in non-clinical settings for its role in cellular lifecycle research and biological signaling models
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Lien S, Larsson AK, Mannervik B
Macrophage subsets (MAC.1, MAC.2) were distinguished by high expression of CD68, CEBPB , and FCER1G , while a third cluster (Inf.MAC) expressed NLRP3 and showed an inflammatory, cytokine-enriched, and pro-angiogenic profile with markers like IL1B and CCL3
Some of these modifications might stabilize the interaction between the glutathione moiety at the scaffold site and the ironsulfur cluster
