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To conduct pull-down experiments for proteomic analysis of interacting proteins, we modified the macrocycles to include a FLAG-tag

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We would recommend seeing your GP for further information

The IRAP inhibitor 48 was the best inhibitor in a second series of bioisosteric diaminobenzoic acid inhibitors but was both less potent and selective as compared 47 (Papakyriakou et al., 2015)

Kim LC, Song L, Haura EB

This can occur in people who have certain medical conditions or who are on certain medications