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Moreover, GLP-1 promotes neurogenesis by reducing inflammation and decreasing the expression of proinflammatory cytokines IL-6, IL-10, and microglial activation (25)
Weeks 34: 2 mg once weekly (Increase only if early GI symptoms are mild and stable) Weeks 58 : 4 mg once weekly Weeks 912: 8 mg once weekly Week 13+: 12 mg once weekly (Only escalate to higher doses if indicated and previous doses were well tolerated) Balanced schedule: Standard trial-inspired ramp This schedule follows a typical balanced titration pace similar to what many clinical trials use
This potentiation was also seen with other Ca 2+ mediated secretagogues
mTORC1, the maestro of cell metabolism and growth
If any persistent side effects occur, discontinue use and consult a doctor
Pharmaceutics 13 , 902 (2021)
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